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HEALTH NEWSLETTER

Special Report on GOUT - 4th Updated Edition


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Here are some FACTS relating to GOUT

JUST WHAT IS GOUT?
Gout is the body's reaction to irritating needle-like crystal deposits between the bones in a joint. It is an inflammatory problem that can strike without warning with intense pain and usually in the joint of the big toe. But, it may also include the ankles, heels, instep, knees, elbows, hips, thumbs, or fingers. It can make walking an impossibility. With prompt treatment, the pain and inflammation should disappear after a few days, but can return at any time.

The inflammation results from the body producing too much uric acid or not eliminating it properly. Uric acid comes from the break down of purine or waste products in the body. The kidneys may not be filtering properly and when uric acid becomes too concentrated, it forms the crystals.

Hyperuricemia is the term used for having an overabundance of uric acid present in the system. This person has not necessarily developed gout - but, may have a tendency to do so.

It is the most common inflammatory type of arthritis in men over thirty years old. Some reports indicate there are some sufferers who have a hereditary predisposition to the ailment. Repeat attacks within one year are common if the body's uric acid level is not kept under control.

Women may experience gout, but it is uncommon. If it develops at all, it is more likely to develop after menopause. It is also very rare in children.

Although Gout is considered a form of Arthritis, it is different than Pseudogout (also called Gouty Arthritis or false gout). It has similar pain, but the uric acid issue is not the culprit. This type gout involves deposits of calcium. It is more common after age sixty in both sexes.

People with regular Chronic gout may find tiny, hard lumps accumulating over time in the soft flesh of the hands, feet, or earlobes. These deposits, called tophi, are chalky-white accumulations of uric acid crystals that can eventually cause aching, stiffness, and protrusions. Tophi does not usually appear until 10 or 12 years after the first attack. This is where permanent damage has been caused to joints or kidneys.

If uric acid deposits form in the kidneys, they can lead to painful and potentially dangerous kidney stones (a condition called urate, or gouty nephropathy). Some level of Kidney dysfunction will likely be present in about 90 percent of those with uric acid deposits. There is a higher risk for kidney stones. There is also some concern that left untreated, kidney failure may result.

SYMPTOMS

* Sudden intense pain in a joint, typically the big toe, ankle or knee.
* Swelling, inflammation, and a feeling that the joint is very hot.
* In extreme cases, alternating chills and fever.
* Usually strikes unexpectedly and may recur, but symptoms typically do not last more than a week.

CAUSES
Gout is brought on by an excessively high level of uric acid in the blood. Uric acid is essential to the digestive process, and the excess is dissolved in the blood, filtered through the kidneys and eliminated in urine.

Many gout sufferers are having a problem with concentrates of uric acid due to the inability to excrete it properly. It appears that a small percentage are over producing uric acid, while another small percentage may be experiencing an enzyme defect that hinders the way the body breaks down purine.

Details for the precise mechanism that causes gout to develop is somewhat obscure. However, the disorder is often associated with an injury or surgical procedure, periods of stress, or reactions to alcohol (malt liquors and wines) and certain drugs, including antibiotics. Diets high in purine, fats and refined carbohydrates are common among those that suffer with this problem. Its incidence is not usually affected by climate or season. However, some reports indicate that deposits develop in the extremities where the pH factor and a lower body temperature are present and this can affect the saturation point of uric acid. Since uric acid is highly insoluble, a pH factor of 7.4 and above and also a lower body temperature will increase the risk factor.

Gout may also occur as a secondary problem to other disorders. It can be brought on by some forms of cancers and tumors. Diuretic therapy for hypertension/high blood pressure and the common low-dose aspirin therapy can be other causes since this reduces uric acid excretion. Research shows that there may be a relation between gout and kidney disorders, enzyme deficiencies, and lead poisoning. Lead poisoning can be linked to water source and other environmental issues such as those found in the air. Enzymes are needed to break down purine and many diets and vitamins are deficient in enzymes. Gout may also accompany psoriasis or anemia.

Pseudogout, or false gout/gouty arthritis is normally a less painful condition caused by calcium crystals. It does involve crystals forming in one or more joints. There can be great inflammation and pain - also swelling in the joint. Pseudo-gout usually has crystals forming in the large joints such as the knees, wrists and ankles. In more severe cases, surgery is used - followed by cortisone injections.

Regarding this type gout, X-rays or an MRI of the joints may be used in making a diagnoses. It may show the deposit of calcium in the cartilage. But it will usually require removal of fluid from the involved joint to be sure. Polarized light used with a microscope may help to identify the crystals of those with Pseudo-Gout.

Special Note: If symptoms last longer than 10 days and you have a history of a tick bite or you have been in an area where tick bites are possible or you have additional symptoms that do not respond to normal treatment, see your doctor for other possibilities. Lyme has been mis-diagnosed for other ailments such as gout and arthritis. For more information on Lyme
Click here: http://www.theolivebranch.com/news/lyme.htm

WHAT ABOUT SMOKING and GOUT?
Tobacco does contain thousands of chemical constituents. It can restrict the peripheral blood vessels which can contribute to problems with circulation. Carbon monoxide binds to hemoglobin, interfering with the transport of oxygen. In addition, there is an increased development of cholesterol deposits to further hinder the circulatory system.

Without enough oxygen and a slowing of blood flow, in theory....that could be a problem for someone with gout. Because, flushing the system of uric acid from the blood stream is a must to avoid the uric acid crystals from forming.

There are many chemical reactions that take place when the toxins from smoke enter the lungs and absorb into the blood stream and other tissue areas.

The scariest thing is the overall danger to health. Most people are not aware of the ingredients in tobacco like carbon monoxide, benzene, cyanide, ammonia, nitrosamines, vinyl chloride, radioactive particles and other carcinogens and irritants. This can really create a health danger to those who smoke and those who are breathing the second hand smoke.

WHAT CAN a GOUT SUFFERER DO?
Of course the first order of business for any gout sufferer is to ease the pain! Clothing or other covering may only aggravate the discomfort of the swollen, sensitive joint, so some physicians advise keeping the affected area exposed, even during sleep. Doctors generally recommend an oral pain-killer and possibly a prescribed non-steroid anti-inflammatory drug or NSAID.

There are many pharmaceuticals that can inhibit or deplete absorption of particular nutrients. So, your medical professional may suggest supplementing along with conventional medications. There are some gout suffers that have found DMSO or MSM lotions or creams to be very helpful for pain issues. DMSO has an odor. So, MSM is a nicer alternative.

In spite of extreme pain at onset, regular gout normally responds well to prompt treatment. Reports indicate that mild cases may be controlled by diet and exercise alone. Chronic attacks of gout, however, may require a long-term treatment regimen and diet changes to prevent damage to bone, tendons, ligaments, cartilage and kidneys.

After the initial discomfort is relieved, it is helpful to keep the body's level of uric acid in balance. Even without conventional or alternative treatments to relieve pain and reduce inflammation, the symptoms usually diminish in a few days or possibly up to a week.

All incidents of suspected gout should be diagnosed by a doctor. Left untreated, uric acid deposits can eventually cause irreversible damage to the kidneys and other joints and tissues. Blood and urine tests during routine checkups may help to signal potential susceptibility to gout attack.

Conventional medicines sometimes used are ibuprofen or naproxen available in prescription or over-the-counter versions. Acetaminophen appears to be less effective for this purpose. Non-Steroidal anti-inflammatories (NSAID) such as Indomethacin or Naproxen may be prescribed. In the book, "MSM, The Natural Solution for Pain", it says, "NSAIDs work by blocking the action of enzymes that help produce inflammatory compounds. At the same time, however, the drugs also inhibit enzymes that produce components of cartilage." There are other side effects associated with use of NSAIDs and other painkillers. Caution is urged about long term use.

Allopurinol should be limited to those with tests that show continuous high levels of uric acid production. Oddly enough, reports indicate that it can actually bring on a gout attack in some people! Drug interactions may include oral meds for diabetes or some types of chemotherapy. There are side effects mentioned in the two Books, "Prescription for Nutritional Healing" and "Smart Medicine for Healthier Living". They include: skin eruptions, inflammation of blood vessels or blood abnormalities, nausea, vomiting, diarrhea, muscle weakness, abdominal pain or gastro-intestinal disturbances and liver damage or toxicity. Treatment should be carefully monitored - especially if you have kidney or liver problems.

Colchicine has been prescribed to alleviate acute attacks and prevent further attacks at low doses of 0.6mg per day. Many patients may not be able to tolerate enough to do them any good without getting gastro-intestinal side effects. Some reports indicate that this drug can cause toxicity, especially when taken in high doses or for prolonged periods. The Encyclopedia of Natural Medicine has a stern warning, saying, "Colchicine may also cause bone marrow depression, hair loss, liver damage, depression, seizures, respiratory depression, and even death." Following are some web sites with more information on Colchicine:
http://www.geocities.com/RainForest/Vines/2259/colchicine.htm#Toxicity
http://biotech.icmb.utexas.edu/botany/colch.html

Probenicid is another prescribed drug that increases excretion of uric acid and should be taken with lots of water for the best function. Good Kidney function is very important for proper elimination while taking this. Side effects can be rash, nausea, vomiting and diarrhea.

Low doses of aspirin, which may have been recommended for other conditions, can slow the elimination of uric acid and it may be recommended by a medical professional to suspend its use in this case. Diuretics may also increase uric acid in the blood.

Steroids can be given by mouth or injection to reduce pain and inflammation in severe attacks or chronic cases. However, steroids such as hydrocortisone can have undesirable side effects in some patients. They can depress the immune system and the adrenal glands can experience additional stress. Most doctors will use in the lowest dose possible for only short periods of time.

It is advisable to investigate reliable sources to see if there are any potential interactions or side effects with any medications you take .....prescribed, over-the-counter or herbals. Some pharmaceuticals can even deplete particular vitamins or minerals that are necessary for good health. Ask lots of questions, because the more information you have, the better decision you can make on a good health regimen.

Keeping the body's level of uric acid in balance can be helped through careful diet planning. A diet that limits protein-rich foods, especially those high in purine, is a must for gout sufferers. The commonly reported foods to avoid include organ meats such as liver; shellfish, fatty fish such as sardines, herring, and anchovies; asparagus, mushrooms and spinach; poultry; red meats and meat extracts such as gravies and bouillon; pork; yeast and yeast products; and most legumes or dry beans or peas. There are some protein foods that are considered lower in purines that should be used in moderation or limited.

Foods that appear to be safer at avoiding the process that brings on gout includes complex carbohydrates, particularly from cereals (not oatmeal). Other foods that are considered safer are eggs and dairy, seeds and nuts, pasta, whole grain or rye breads, and tomatoes, fruits, vegetables (but, not spinach, asparagus, cauliflower, lentils, legumes or mushrooms) .

Another site on Gout from "Nutraceuticals In the News"
http://nutrinus.com/083100.htm#Gout

Also, a high intake of filtered water and non-alcoholic liquids is recommended to help the body flush toxins and reduce uric acid levels.

Alternative therapy choices might include herbs and natural nutritional products. Another therapy might include an herbal tea to help stimulate the elimination of uric acid. Herbal teas should not be used if colchicine has been prescribed. The ideal regimen of supplements should include a good assortment of vitamins, minerals, antioxidants, fiber and digestive enzymes.

Essential oils have been used in cool or cold compresses to reduce pain and discomfort. These may also be used in the bath. As the pain and swelling reduce, perhaps oils that bring local warmth can be considered. As we have already mentioned, MSM is also reported as useful in reducing pain.

Several authorities report some favorable results for chronic gout patients by having them eat fresh cherries, 8 ounces or more a day, or drinking concentrated cherry juice various times of the day on a daily basis. Fresh Strawberries and blueberries contain properties that might have similar benefits.

CALL YOUR DOCTOR IF:

* Severe pain in a joint recurs or lasts more than a few days, especially if the pain is accompanied by chills or fever; you may be experiencing the early signs of rheumatoid arthritis or, in rare cases, lead poisoning.

*Symptoms of gout increase or other side effects occur while you are taking allopurinol (or other drugs) to reduce uric acid production or colchicine to relieve pain. A pharmacist should be able to give you information on any potential problems associated with pharmaceuticals.


RESOURCES

Gout Sufferer Testimony - http://www.theolivebranch.com/goutt.htm

Diet and Other Nutritional Information - http://www.theolivebranch.com/goutdiet.htm

General Gout Info - http://www.theolivebranch.com/gout.htm

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The more information you have, the better decision you can make on a good health regimen. We hope our Newsletter has been helpful. We're always available to answer your questions.

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The Culbreths

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Please note: the information contained herein has been compiled from various sources. The above statements have not been evaluated by the U.S. Food and Drug Administration. We make no claims, either expressed or implied, that any products mentioned in this newsletter will cure or prevent disease, replace prescription medication, or supersede sound medical advice.